陈贵泉实验室

1.    Cheng S, Liu T, Xia Y, Hou J, Huang C, Zou X, Shi Y, Zheng Y, Hu Y, Lu J and Chen G*. Conditional inactivation of Pen-2 in the developing neocortex leads to rapid switch of apical progenitors to basal progenitors. In submission, 2018..

2.    Yang S, Chang Y, Zhang H, Yu X, Shang W, Chen G, Chen DY and Gu Z. Enrichment of phosphorylated peptides with metal−organic framework nanosheets for serum profiling of diabetes and phosphoproteomics analysis. Analytical Chemistry, 2018; 90:13796−13805..

3.    Wu DM, Wen X, Wang YJ, Han XR, Wang S, Shen M, Fan XH, Zhuang J, Zhang ZF, Shan Q, Li MQ, Hu B, Sun CH, Lu J*, Chen G* and Zheng YL*. Effect of microRNA-186 on oxidative stress injury of neuron by targeting IL 2 through the JAK-STAT pathway in a rat model of Alzheimer’s disease. Journal of Cellular Physiology Doi:10.1002/jcp.26297.

4.    Zhang T, Shi Z, Wang Y, Wang L, Zhang B, Chen G, Wan Q, Chen L. Akt3 deletion in mice impairs spatial cognition and hippocampal CA1 long long-term potentiation through downregulation of mTOR. Acta Physiologica, 2018; DOI: 10.1111/apha.13167.

5.    Yang S, Yu H, Wang Z, Liu H, Zhang H, Yu X, Shang W, Chen G and Gu Z*. An exfoliated 2-D egyptian blue nanosheet for highly selective enrichment of multi-phosphorylated peptides in mass spectrometric analysis (Cover story). Chem. Eur. J.2018; 24: 2109-2116. DOI: 10.1002/chem.201704138.

6.    Zhou J^#, Wang X^#, Zhou L, Zhou L, Xu F, Su L, Wang H, Jia F, Xu F, Chen G, De Zeeuw C and Shen Y*. Ablation of TFR1 in Purkinje cells inhibits mGlu1 trafficking and impairs motor coordination, but not autistic-like behaviors. Journal of Neuroscience, 2017; 37: 11335–11352. DOI: 10.1523/JNEUROSCI. 1223-17.

7.    Liu T^#, Ye X^#, Zhang J, Yu T, Cheng S, Zou X, Xu Y, Chen G* and Yin Z*. Increased adult neurogenesis associated with reactive astrocytosis occurs prior to neuron loss in a mouse model of neurodegenerative disease. CNS Neuroscience & Therapeutics, 2017; 23: 885–893.

8.    Xu C, Yu L, Hou J, Jackson RJ, Wang H, Huang C, Liu T, Zou X, Morris RGM, Spires-jones TL, Yang Z, Yin Z*, Xu Y* and Chen G*. Conditional deletion of PDK1 in the forebrain causes neuron loss and increased apoptosis during cortical development. Front. Cell. Neurosci., 2017. DOI: 10.3389/fncel.2017.00330.

9.    Wang H, Zhang B, Zhang T, Wang L, Zou X, Xu Y, Chen L, Chen G*. Impaired spatial learning is associated with disrupted integrity of the white matter in Akt3 knockout mice. CNS Neuroscience & Therapeutics, 2017; 23: 99–102.

10.   He X^#, Li Y^#, Kalyanaraman C, Qiu L, Chen C, Xiao Q, Liu W, Zhang W, Yang J, Chen G, Jacobson MP, Shi Y*. GluA1 signal peptide determines the spatial assembly of heteromeric AMPA receptors. Proc Natl Acad Sci USA, 2016；113：E5645-5654.

11.   Hou J, Cheng S, Chen L, Wang Q, Wang H, Shi Y, Xu Y, Yin Z, Chen G*. Astroglial activation and tau hyperphosphorylation precedes to neuron loss in a neurodegenerative mouse model. CNS Neuroscience & Therapeutics, 2016; 22: 244–247.

12.   Wang L^#, Cheng S^#, Yin Z, Xu C, Hou J, Lu S, Yu T, Zou X, Peng Y, Xu Y*, Yang Z*, Chen G*. Conditional inactivation of Akt three isoforms causes tau hyperphosphorylation in the brain. Molecular Neurodegeneration, 2015; DOI：10.1186/s13024-015-0030.

13.   Cheng S^#, Hou J^#, Zhang C, Xu C, Wang L, Zou X, Yu, H, Shi Y, Yin Z*, Chen G*. Minocycline reduces neuroinflammation but does not ameliorate neuron loss in a mouse model of neurodegeneration. Scientific Reports, 2015; 5,10535，DOI:10.1038.

14.   Cheng S, Zhang C, Xu C, Wang L, Zou X, Chen G*. Age-dependent neuron loss is associated with impaired adult neurogenesis in forebrain neuron-specific Dicer conditional knockout mice. The International Journal of Biochemistry & Cell Biology, 2014; 57:186-96.

15.   Meng H, Chen G, Gao H, Shi Y, Liu C*. The emerging nexus of active DNA demethylation and mitochondrial oxidative metabolism in post-mitotic neurons. Int. J. Mol. Sci., 2014; 15: 22604–25.