陈贵泉实验室

近五年发表的论文 (*, Corresponding author)

1.  Shao C, Yuan J, Liu Y, Wang X, Gu J, Chen G, Zhu H and Qian Y*. Epileptic brain fluorescent imaging reveals apigenin can relieve the myeloperoxidase- mediated oxidative stress and inhibit ferroptosis. Proc. Natl. Acad. Sci. USA 2020, Accepted.

2.   Huang C, Liu T, Wang Q, Hou W, Zhou C, Song Z, Shi YS, Gao X, Chen G*, Yin Z* and Hu Y*. Loss of PP2A disrupts the retention of radial glial progenitors in the telencephalic niche to impair the generation of late-born neurons during cortical development. Cerebral Cortex 2020, DOI: 10.1093/cercor/bhaa042.

3.   Ma X, Wang Y, Hua J, Xu C, Yang T, Yuan J, Chen G*, Guo Z* and Wang X*. Aβ-sheet- targeted theranostic agent for diagnosing and preventing aggregation of pathogenic peptides in Alzheimer’s disease. Science China Chemistry 2020, 63: 73-82.

4.   Cheng S, Liu T, Hu Y, Xia Y, Hou J, Huang C, Zou X, Shi Y, Zheng Y, Lu J* and Chen G*. Conditional inactivation of Pen-2 in the developing neocortex leads to rapid switch of apical progenitors to basal progenitors. Journal of Neuroscience 2019, 39: 2195-2207.

5.   Wu DM, Zheng Z, Wang S, Wen X, Han X, Wang Y, Shen M, Fan X, Zhang ZF, Shan Q, Li M, Hu B, Zheng YL*, Chen G* and Lu J*. Association between plasma macrophage migration inhibitor factor and deep vein thrombosis in patients with spinal cord injuries. Aging-US 2019; 11(8): 2447-2456.

6.   Li Y, Duan G, Sun J, Wu D, Ye C, Zang Y, Chen G, Shi Y, Wang J, Zhang W and Shi YS*. Neto proteins regulate gating of the kainate-type glutamate receptor GluK2 through two binding sites. Journal of Biological Chemistry 2019.

7.  Yang S, Chang Y, Zhang H, Yu X, Shang W, Chen G, Chen DY and Gu Z. Enrichment of phosphorylated peptides with metal−organic framework nanosheets for serum profiling of diabetes and phosphoproteomics analysis. Analytical Chemistry, 2018; 90:13796−13805.

8.   Wu DM, Wen X, Wang YJ, Han XR, Wang S, Shen M, Fan XH, Zhuang J, Zhang ZF, Shan Q, Li MQ, Hu B, Sun CH, Lu J*, Chen G* and Zheng YL*. Effect of microRNA-186 on oxidative stress injury of neuron by targeting IL 2 through the JAK-STAT pathway in a rat model of Alzheimer’s disease. Journal of Cellular Physiology, 2018. Doi:10.1002/jcp.26297.

9.   Zhang T, Shi Z, Wang Y, Wang L, Zhang B, Chen G, Wan Q, Chen L*. Akt3 deletion in mice impairs spatial cognition and hippocampal CA1 long long-term potentiation through downregulation of mTOR. Acta Physiologica, 2018; DOI: 10.1111/apha.13167.

10. Zhou J, Wang X, Zhou L, Zhou L, Xu F, Su L, Wang H, Jia F, Xu F, Chen G, De Zeeuw C and Shen Y. Ablation of TFR1 in Purkinje cells inhibits mGlu1 trafficking and impairs motor coordination, but not autistic-like behaviors. Journal of Neuroscience, 2017; 37: 11335–11352.

11. Liu T, Ye X, Zhang J, Yu T, Cheng S, Zou X, Xu Y, Chen G* and Yin Z*. Increased adult neurogenesis associated with reactive astrocytosis occurs prior to neuron loss in a mouse model of neurodegenerative disease. CNS Neuroscience & Therapeutics, 2017; 23: 885–893.

12. Xu C, Yu L, Hou J, Jackson RJ, Wang H, Huang C, Liu T, Zou X, Morris RGM, Spires-jones TL, Yang Z, Yin Z*, Xu Y* and Chen G*. Conditional deletion of PDK1 in the forebrain causes neuron loss and increased apoptosis during cortical development. Frontiers in Cellular Neuroscience, 2017. DOI: 10.3389/fncel.2017. 00330.

13. Wang H, Zhang B, Zhang T, Wang L, Zou X, Xu Y, Chen L, Chen G*. Impaired spatial learning is associated with disrupted integrity of the white matter in Akt3 knockout mice. CNS Neuroscience & Therapeutics, 2017; 23: 99–102.

14. He X, Li Y, Kalyanaraman C, Qiu L, Chen C, Xiao Q, Liu W, Zhang W, Yang J, Chen G, Jacobson MP, Shi Y. GluA1 signal peptide determines the spatial assembly of heteromeric AMPA receptors. Proc. Natl. Acad. Sci. USA, 2016; 113:E5645-5654.

15. Wang L, Cheng S, Yin Z, Xu C, Hou J, Lu S, Yu T, Zou X, Peng Y, Xu Y*, Yang Z*, Chen G*. Conditional inactivation of Akt three isoforms causes tau hyperphosphorylation in the brain. Molecular Neurodegeneration, 2015; DOI：10.1186/s13024-015-0030.

16. Cheng S, Hou J, Zhang C, Xu C, Wang L, Zou X, Yu, H, Shi Y, Yin Z*, Chen G*. Minocycline reduces neuroinflammation but does not ameliorate neuron loss in a mouse model of neurodegeneration. Scientific Reports, 2015; 5,10535，DOI:10.1038.